Neo peptide engineering with A.I.Ivan Jacobs
Fill in amino acid sequence and let our tool generate the peptide structure. Click on predict HLA to get all the HLA structures annotated with predictions by our model. The labels strong, weak and no binding are indicative of the binding affinity of the peptide with the HLA. Select the HLA of choice and the complex is updated. You are now able to do the same for the TCR. Here the model takes into account the previously created peptide HLA complex. Now you can predict the folding of the peptide in the HLA-TCR complex and the affinity of the complex.